Study Reveals that Chronic Stress and Depression Can Trigger Bone Loss

ache-19005_1920Anxiety disorders are the most common mental illness in the U.S., affecting 40 million adults that are 18 years and older. Not only does this account for 18 percent of the U.S. population, nearly one-half of those diagnosed with depression are also diagnosed with an anxiety disorder (or vice versa). While chronic stress and depression stem from anxiety disorders, a recent study has shed more light on how these two mental illnesses can lead to bone loss.


The results have been announced by Holger Henneicke of the University of Sydney at the 43rd annual congress of the European Calcified Tissue Society (ECTS). During the event, Henneicke described how the study examined the impact of chronic stress on skeletal metabolism and structure in mice. The study specifically examined the signals of a particular hormone being disrupted, which was suspected as being the link between chronic stress and bone loss.


“We know stress and depression are linked to poor bone health but not how one results in the other, so we set out to determine the role played by stress hormones, known as glucocorticoids, in the cells which synthesize bone,” said Dr. Henneicke.


Dr. Henneicke also stated, “Eight-week-old male and female mice were exposed to chronic, but mild stress. In some mice, the glucocorticoid signaling was selectively disrupted in bone-forming osteoblasts, while their littermates were left ‘wild.’”


Henneicke’s study concluded that the male mice experienced bone loss due to chronic stress, while the female mice did not have the same results. He also specified that further research would need to be conducted to understand how females are influenced by chronic stress.


For those who do suffer from chronic stress and depression, the American Psychological Association provides a few helpful tips to keep in mind when experiencing feelings of anxiety or overwhelming hopelessness:


  • Set limits to your projects and commitments
  • Tap into your support system
  • Make one health-related commitment
  • Enhance your sleep quality
  • Strive for a positive outlook
  • Seek additional help


Even though this study is newer in the bone health world and additional research is needed to truly validate a link between the diseases, a person who struggles with chronic stress and depression should be mindful of how this can affect their overall wellbeing. For those individuals who do experience pain in their back, bone fractures or a loss of height, OsteoStrong is non-invasive, wellness solution that is scientifically proven to dramatically and painlessly increase bone density in just a few months. To learn more about recovering your bone density in less than 10 minutes once a week, visit